Pseudomonas aeruginosa RP73, M062_23255 (murD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00639
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008764 UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00639
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016881 acid-amino acid ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53244
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00639
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009058 biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53244
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008360 regulation of cell shape
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00639
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0051301 cell division
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00639
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other RP73 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG prp00550 Peptidoglycan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp00471 D-Glutamine and D-glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG prp01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF51984 MurCD N-terminal domain - - 11 97 5.62E-15
PANTHER PTHR43692 UDP-N-ACETYLMURAMOYLALANINE--D-GLUTAMATE LIGASE IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD 10 447 0.0
Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD 8 442 33.943981
Gene3D G3DSA:3.40.1190.10 - IPR036565 Mur-like, catalytic domain superfamily 98 305 1.2E-53
Pfam PF02875 Mur ligase family, glutamate ligase domain IPR004101 Mur ligase, C-terminal 307 380 1.9E-7
Gene3D G3DSA:3.40.50.720 - - - 7 96 6.2E-20
Pfam PF08245 Mur ligase middle domain IPR013221 Mur ligase, central 114 285 2.3E-25
NCBIfam TIGR01087 JCVI: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD 12 445 3.4E-117
SUPERFAMILY SSF53244 MurD-like peptide ligases, peptide-binding domain IPR036615 Mur ligase, C-terminal domain superfamily 305 447 7.1E-47
Gene3D G3DSA:3.90.190.20 - IPR036615 Mur ligase, C-terminal domain superfamily 311 448 8.4E-43
SUPERFAMILY SSF53623 MurD-like peptide ligases, catalytic domain IPR036565 Mur-like, catalytic domain superfamily 100 303 2.62E-52

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.