Pseudomonas aeruginosa RP73, M062_26465 (cvrA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0015297 antiporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00999
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00999
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006813 potassium ion transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01075
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055085 transmembrane transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00999
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008324 cation transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02080
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050660 flavin adenine dinucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF56176
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0015386 potassium:proton antiporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01075
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006884 cell volume homeostasis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01075
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:1902600 proton transmembrane transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00999
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006812 cation transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00999
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Membrane proteins Other RP73 genes in this class
Transport of small molecules Other RP73 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF03471 Transporter associated domain IPR005170 Transporter-associated domain 495 569 1.6E-10
Gene3D G3DSA:3.30.70.1450 - IPR036721 Regulator of K+ conductance, C-terminal domain superfamily 408 484 1.1E-12
Pfam PF02080 TrkA-C domain IPR006037 Regulator of K+ conductance, C-terminal 421 483 2.0E-11
Gene3D G3DSA:3.30.465.10 - IPR016169 FAD-binding, type PCMH, subdomain 2 496 574 2.2E-7
SUPERFAMILY SSF56176 FAD-binding/transporter-associated domain-like IPR036318 FAD-binding, type PCMH-like superfamily 497 569 3.54E-8
Pfam PF00999 Sodium/hydrogen exchanger family IPR006153 Cation/H+ exchanger 15 386 8.7E-57
SMART SM01091 CorC_HlyC_2 IPR005170 Transporter-associated domain 492 571 1.3E-12
Gene3D G3DSA:1.20.1530.20 - IPR038770 Sodium/solute symporter superfamily 7 391 7.2E-20
Hamap MF_01075 K(+)/H(+) antiporter NhaP2 [nhaP2]. IPR023729 K(+)/H(+) antiporter NhaP2 1 574 51.641262
PANTHER PTHR32507 NA(+)/H(+) ANTIPORTER 1 - - 1 553 0.0
SUPERFAMILY SSF116726 TrkA C-terminal domain-like IPR036721 Regulator of K+ conductance, C-terminal domain superfamily 411 483 3.53E-11

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.