Pseudomonas aeruginosa RP73, M062_28735

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa RP73
GCF_000414035.1|latest
Locus Tag
M062_28735
Name
Replicon chromosome
Genomic location 6220503 - 6221417 (- strand)

Cross-References

RefSeq YP_008136115.1
GI 514412554
Entrez 15963485
NCBI Locus Tag M062_28735

Product

Feature Type CDS
Coding Frame 1
Product Name
NAD-dependent dehydratase
Synonyms
Evidence for Translation
Charge (pH 7) -1.65
Kyte-Doolittle Hydrophobicity Value -0.141
Molecular Weight (kDa) 33.9
Isoelectric Point (pI) 6.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6X3B OXIDOREDUCTASE 05/21/20 Structure of RMD from Pseudomonas aeruginosa complexed with NADPH Pseudomonas aeruginosa 1.91 X-RAY DIFFRACTION 99.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 636 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005000 (385 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: M062_28735

Human Homologs

Ensembl 110, assembly GRCh38.p14
GDP-mannose 4,6-dehydratase [Source:HGNC Symbol;Acc:HGNC:4369]
E-value: 5.6e-14
Percent Identity: 27.4
Ensembl 110, assembly GRCh38.p14
GDP-mannose 4,6-dehydratase [Source:HGNC Symbol;Acc:HGNC:4369]
E-value: 5.6e-14
Percent Identity: 27.4

References

No references are associated with this feature.