Pseudomonas entomophila L48, PSEEN4392 (guaA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006164 purine nucleotide biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00958
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003922 GMP synthase (glutamine-hydrolyzing) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00958
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006177 GMP biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00958
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00958
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc guanosine ribonucleotides <i>de novo</i> biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pen00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pen01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.30.300.10:FF:000002 GMP synthase [glutamine-hydrolyzing] - - 411 525 4.8E-54
SUPERFAMILY SSF52402 Adenine nucleotide alpha hydrolases-like - - 197 420 1.52E-57
Pfam PF00117 Glutamine amidotransferase class-I IPR017926 Glutamine amidotransferase 12 198 3.9E-35
NCBIfam TIGR00888 JCVI: glutamine-hydrolyzing GMP synthase, N-terminal domain IPR004739 GMP synthase, glutamine amidotransferase 10 205 6.1E-77
PRINTS PR00096 Glutamine amidotransferase superfamily signature - - 177 190 4.1E-7
PRINTS PR00096 Glutamine amidotransferase superfamily signature - - 54 63 4.1E-7
Gene3D G3DSA:3.40.50.880 - IPR029062 Class I glutamine amidotransferase-like 9 206 5.4E-52
NCBIfam TIGR00884 JCVI: glutamine-hydrolyzing GMP synthase, C-terminal domain IPR001674 GMP synthase, C-terminal 212 525 0.0
PANTHER PTHR11922 GMP SYNTHASE-RELATED - - 10 525 0.0
PRINTS PR00096 Glutamine amidotransferase superfamily signature - - 81 92 4.1E-7
FunFam G3DSA:3.40.50.620:FF:000001 GMP synthase [glutamine-hydrolyzing] - - 209 410 6.5E-101
PRINTS PR00097 Anthranilate synthase component II signature - - 54 63 6.6E-6
Pfam PF02540 NAD synthase IPR022310 NAD/GMP synthase 215 289 2.7E-7
CDD cd01997 GMP_synthase_C IPR001674 GMP synthase, C-terminal 230 524 0.0
SUPERFAMILY SSF54810 GMP synthetase C-terminal dimerisation domain - - 405 525 2.09E-49
SUPERFAMILY SSF52317 Class I glutamine amidotransferase-like IPR029062 Class I glutamine amidotransferase-like 5 204 1.52E-54
Pfam PF00958 GMP synthase C terminal domain IPR001674 GMP synthase, C-terminal 433 524 1.6E-40
Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. IPR022955 GMP synthase 7 525 55.416702
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 209 410 7.7E-78
CDD cd01742 GATase1_GMP_Synthase IPR004739 GMP synthase, glutamine amidotransferase 10 198 2.63424E-97
PRINTS PR00097 Anthranilate synthase component II signature - - 81 92 6.6E-6
FunFam G3DSA:3.40.50.880:FF:000001 GMP synthase [glutamine-hydrolyzing] - - 7 206 2.0E-85
PRINTS PR00097 Anthranilate synthase component II signature - - 177 190 6.6E-6
Gene3D G3DSA:3.30.300.10 - - - 411 525 1.2E-48

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.