Pseudomonas stutzeri ATCC 17588 = LMG 11199, PSTAB_0168 (polA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006139 nucleobase-containing compound metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00474
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008408 3'-5' exonuclease activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00474
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00279
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00474
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00482
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003887 DNA-directed DNA polymerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00482
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02739
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006261 DNA-dependent DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00868
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG psz00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psz03420 Nucleotide excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psz03410 Base excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psz00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psz03030 DNA replication 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psz01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG psz03440 Homologous recombination 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:1.10.150.20:FF:000003 DNA polymerase I - - 170 265 3.6E-26
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 641 663 2.4E-78
Gene3D G3DSA:3.40.50.1010 - - - 1 169 8.5E-54
SMART SM00474 35exoneu6 IPR002562 3'-5' exonuclease domain 315 502 1.6E-41
Gene3D G3DSA:3.30.420.10 - IPR036397 Ribonuclease H superfamily 312 527 1.1E-73
CDD cd09898 H3TH_53EXO IPR020045 DNA polymerase I-like, H3TH domain 170 250 2.05951E-28
Pfam PF00476 DNA polymerase family A IPR001098 DNA-directed DNA polymerase, family A, palm domain 536 912 0.0
PANTHER PTHR10133 DNA POLYMERASE I IPR002298 DNA polymerase A 305 914 0.0
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 664 679 2.4E-78
SUPERFAMILY SSF56672 DNA/RNA polymerases IPR043502 DNA/RNA polymerase superfamily 507 914 0.0
SUPERFAMILY SSF47807 5' to 3' exonuclease, C-terminal subdomain IPR036279 5'-3' exonuclease, C-terminal domain superfamily 168 289 6.73E-28
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 686 709 2.4E-78
SUPERFAMILY SSF88723 PIN domain-like IPR029060 PIN-like domain superfamily 5 167 2.35E-53
NCBIfam TIGR00593 JCVI: DNA polymerase I IPR018320 DNA polymerase 1 6 914 0.0
FunFam G3DSA:1.20.1060.10:FF:000001 DNA polymerase I - - 528 644 2.1E-38
Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal 6 167 1.3E-50
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 831 847 2.4E-78
CDD cd06139 DNA_polA_I_Ecoli_like_exo - - 330 524 4.4596E-99
Gene3D G3DSA:1.10.150.20 - - - 695 838 1.4E-114
SMART SM00475 53exo3 IPR002421 5'-3' exonuclease 4 266 1.6E-115
CDD cd09859 PIN_53EXO - - 8 164 2.54187E-79
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 716 729 2.4E-78
FunFam G3DSA:3.40.50.1010:FF:000001 DNA polymerase I - - 1 169 1.9E-69
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 777 788 2.4E-78
SMART SM00482 polaultra3 IPR001098 DNA-directed DNA polymerase, family A, palm domain 672 878 1.4E-114
FunFam G3DSA:1.10.150.20:FF:000002 DNA polymerase I - - 695 838 4.7E-61
SMART SM00279 HhH_4 IPR008918 Helix-hairpin-helix motif, class 2 170 205 2.5E-12
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 740 765 2.4E-78
Gene3D G3DSA:1.20.1060.10 Taq DNA Polymerase; Chain T, domain 4 - - 528 644 3.9E-36
Gene3D G3DSA:1.10.150.20 - - - 170 264 2.4E-24
Pfam PF01612 3'-5' exonuclease IPR002562 3'-5' exonuclease domain 315 501 1.3E-38
Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold IPR020045 DNA polymerase I-like, H3TH domain 168 269 3.4E-26
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 861 874 2.4E-78
FunFam G3DSA:3.30.420.10:FF:000026 DNA polymerase I - - 312 527 2.6E-94
SUPERFAMILY SSF53098 Ribonuclease H-like IPR012337 Ribonuclease H-like superfamily 320 503 1.03E-55
Gene3D G3DSA:3.30.70.370 - - - 650 910 1.4E-114
PRINTS PR00868 DNA-polymerase family A (pol I) signature IPR002298 DNA polymerase A 799 810 2.4E-78
CDD cd08637 DNA_pol_A_pol_I_C - - 533 911 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.