Pseudomonas stutzeri CCUG 29243, A458_05600 (guaA)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0005524	ATP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:cd01742	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006177	GMP biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006164	purine nucleotide biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:cd01997	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0003922	GMP synthase (glutamine-hydrolyzing) activity	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
MetaCyc		guanosine ribonucleotides <i>de novo</i> biosynthesis	InterPro 5.36-75.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion
KEGG	psc01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	psc00230	Purine metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Hamap	MF_00344	GMP synthase [glutamine-hydrolyzing] [guaA].	IPR022955	GMP synthase	8	526	56.071815
Gene3D	G3DSA:3.40.50.880	-	IPR029062	Class I glutamine amidotransferase-like	10	207	1.1E-54
Pfam	PF00117	Glutamine amidotransferase class-I	IPR017926	Glutamine amidotransferase	13	201	3.1E-36
Pfam	PF00958	GMP synthase C terminal domain	IPR001674	GMP synthase, C-terminal	434	525	9.3E-41
NCBIfam	TIGR00888	JCVI: glutamine-hydrolyzing GMP synthase, N-terminal domain	IPR004739	GMP synthase, glutamine amidotransferase	11	206	3.3E-78
NCBIfam	TIGR00884	JCVI: glutamine-hydrolyzing GMP synthase, C-terminal domain	IPR001674	GMP synthase, C-terminal	213	526	0.0
PRINTS	PR00097	Anthranilate synthase component II signature	-	-	55	64	1.9E-5
SUPERFAMILY	SSF54810	GMP synthetase C-terminal dimerisation domain	-	-	406	526	9.29E-50
Gene3D	G3DSA:3.40.50.620	HUPs	IPR014729	Rossmann-like alpha/beta/alpha sandwich fold	210	411	3.7E-77
PANTHER	PTHR11922	GMP SYNTHASE-RELATED	-	-	11	526	0.0
PRINTS	PR00096	Glutamine amidotransferase superfamily signature	-	-	178	191	7.0E-7
CDD	cd01742	GATase1_GMP_Synthase	IPR004739	GMP synthase, glutamine amidotransferase	11	199	3.25957E-97
PRINTS	PR00096	Glutamine amidotransferase superfamily signature	-	-	55	64	7.0E-7
PRINTS	PR00097	Anthranilate synthase component II signature	-	-	82	93	1.9E-5
Pfam	PF02540	NAD synthase	IPR022310	NAD/GMP synthase	216	291	1.6E-7
PRINTS	PR00096	Glutamine amidotransferase superfamily signature	-	-	82	93	7.0E-7
FunFam	G3DSA:3.40.50.880:FF:000001	GMP synthase [glutamine-hydrolyzing]	-	-	8	207	1.8E-86
SUPERFAMILY	SSF52402	Adenine nucleotide alpha hydrolases-like	-	-	198	421	1.48E-57
Gene3D	G3DSA:3.30.300.10	-	-	-	412	526	1.0E-48
PRINTS	PR00097	Anthranilate synthase component II signature	-	-	178	191	1.9E-5
SUPERFAMILY	SSF52317	Class I glutamine amidotransferase-like	IPR029062	Class I glutamine amidotransferase-like	6	205	3.48E-57
FunFam	G3DSA:3.40.50.620:FF:000001	GMP synthase [glutamine-hydrolyzing]	-	-	210	411	2.5E-100
FunFam	G3DSA:3.30.300.10:FF:000002	GMP synthase [glutamine-hydrolyzing]	-	-	412	526	3.5E-54
CDD	cd01997	GMP_synthase_C	IPR001674	GMP synthase, C-terminal	231	525	0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.