Pseudomonas mendocina NK-01, MDS_0648

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004742 dihydrolipoyllysine-residue acetyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006096 glycolytic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0045254 pyruvate dehydrogenase complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016746 transferase activity, transferring acyl groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00198
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG (InterPro) 00020 Citrate cycle (TCA cycle) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pmk00010 Glycolysis / Gluconeogenesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk00620 Pyruvate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00620 Pyruvate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pmk01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00010 Glycolysis / Gluconeogenesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pmk01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pmk00020 Citrate cycle (TCA cycle) 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.559.10 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily 305 547 2.9E-96
CDD cd06849 lipoyl_domain 114 186 6.57217E-20
Gene3D G3DSA:2.40.50.100 2 79 2.1E-22
ProSiteProfiles PS51826 Peripheral subunit-binding (PSBD) domain profile. IPR004167 Peripheral subunit-binding domain 244 281 21.969
CDD cd06849 lipoyl_domain 5 73 1.35133E-20
ProSiteProfiles PS50968 Biotinyl/lipoyl domain profile. IPR000089 Biotin/lipoyl attachment 2 74 25.611
SUPERFAMILY SSF51230 IPR011053 Single hybrid motif 113 203 1.7E-21
Pfam PF00364 Biotin-requiring enzyme IPR000089 Biotin/lipoyl attachment 115 186 3.8E-22
Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain 318 546 3.1E-77
ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site 137 166 -
TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex 96 547 0.0
SUPERFAMILY SSF52777 306 547 4.89E-81
Pfam PF00364 Biotin-requiring enzyme IPR000089 Biotin/lipoyl attachment 5 73 1.3E-20
Gene3D G3DSA:4.10.320.10 IPR036625 E3-binding domain superfamily 243 288 1.1E-19
SUPERFAMILY SSF51230 IPR011053 Single hybrid motif 4 93 2.36E-22
Gene3D G3DSA:2.40.50.100 114 191 1.0E-19
ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site 24 53 -
SUPERFAMILY SSF47005 IPR036625 E3-binding domain superfamily 237 282 1.01E-12
Pfam PF02817 e3 binding domain IPR004167 Peripheral subunit-binding domain 243 278 4.5E-15
ProSiteProfiles PS50968 Biotinyl/lipoyl domain profile. IPR000089 Biotin/lipoyl attachment 113 187 25.791

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.