Pseudomonas mendocina NK-01, MDS_0818
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0004866 | endopeptidase inhibitor activity |
Inferred from Sequence Model
Term mapped from: InterPro:SM01360
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
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| Cellular Component | GO:0005615 | extracellular space |
Inferred from Sequence Model
Term mapped from: InterPro:PF07678
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ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
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Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Gene3D | G3DSA:1.50.10.20 | - | - | - | 1123 | 1381 | 2.0E-33 |
| PANTHER | PTHR40094 | ALPHA-2-MACROGLOBULIN HOMOLOG | - | - | 98 | 175 | 0.0 |
| Gene3D | G3DSA:2.60.40.1930 | - | - | - | 352 | 449 | 1.3E-12 |
| SMART | SM01359 | A2M_N_2_2 | IPR011625 | Alpha-2-macroglobulin, bait region domain | 710 | 858 | 5.0E-38 |
| Pfam | PF01835 | MG2 domain | IPR002890 | Macroglobulin domain | 353 | 445 | 4.9E-19 |
| SUPERFAMILY | SSF48239 | Terpenoid cyclases/Protein prenyltransferases | IPR008930 | Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid | 1127 | 1383 | 1.49E-43 |
| PIRSF | PIRSF038980 | A2M_bac | IPR026284 | Alpha-2-macroglobulin, bacteria | 1 | 1606 | 0.0 |
| Pfam | PF17970 | Bacterial Alpha-2-macroglobulin MG1 domain | IPR040639 | Alpha-2-macroglobulin, MG1 domain | 24 | 128 | 2.0E-48 |
| Pfam | PF17962 | Bacterial macroglobulin domain 6 | IPR041462 | Bacterial Alpha-2-macroglobulin, MG6 domain | 582 | 694 | 8.4E-30 |
| CDD | cd02891 | A2M_like | - | - | 1126 | 1385 | 1.2937E-55 |
| Coils | Coil | Coil | - | - | 1521 | 1541 | - |
| SMART | SM01419 | Thiol_ester_cl_2 | IPR047565 | Alpha-macroglobulin-like, thiol-ester bond-forming region | 1127 | 1156 | 2.3E-5 |
| Pfam | PF07703 | Alpha-2-macroglobulin bait region domain | IPR011625 | Alpha-2-macroglobulin, bait region domain | 711 | 857 | 8.9E-12 |
| Pfam | PF11974 | Bacterial alpha-2-macroglobulin MG3 domain | IPR021868 | Alpha-2-macroglobulin MG3 domain | 254 | 346 | 9.3E-22 |
| Pfam | PF00207 | Alpha-2-macroglobulin family | IPR001599 | Alpha-2-macroglobulin | 926 | 1007 | 1.6E-9 |
| Pfam | PF17972 | Bacterial Alpha-2-macroglobulin MG5 domain | IPR041203 | Bacterial Alpha-2-macroglobulin, MG5 domain | 451 | 576 | 6.4E-42 |
| Pfam | PF17973 | Bacterial Alpha-2-macroglobulin MG10 domain | IPR041246 | Bacterial alpha-2-macroglobulin MG10 domain | 1457 | 1589 | 1.8E-27 |
| Pfam | PF07678 | A-macroglobulin TED domain | IPR011626 | Alpha-macroglobulin-like, TED domain | 1126 | 1236 | 1.1E-9 |
| SMART | SM01360 | A2M_2 | IPR001599 | Alpha-2-macroglobulin | 919 | 1008 | 1.2E-24 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.