Pseudomonas mendocina NK-01, MDS_2415

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02775
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000287 magnesium ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00205
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0030976 thiamine pyrophosphate binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02775
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pmk00620 Pyruvate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.50.970 - - - 355 582 4.2E-47
PANTHER PTHR42981 PYRUVATE DEHYDROGENASE [UBIQUINONE] IPR047211 Pyruvate oxidase/Pyruvate dehydrogenase [ubiquinone]-like 1 579 0.0
CDD cd02014 TPP_POX IPR047212 Pyruvate oxidase POXB-like, PP-binding domain 365 551 9.84803E-79
Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain IPR011766 Thiamine pyrophosphate enzyme, TPP-binding 388 542 1.7E-23
SUPERFAMILY SSF52467 DHS-like NAD/FAD-binding domain IPR029035 DHS-like NAD/FAD-binding domain superfamily 189 356 2.91E-41
Pfam PF00205 Thiamine pyrophosphate enzyme, central domain IPR012000 Thiamine pyrophosphate enzyme, central domain 198 328 1.4E-26
Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain 4 173 4.7E-43
Gene3D G3DSA:3.40.50.970 - - - 1 176 2.2E-48
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 2 175 5.89E-48
CDD cd07039 TPP_PYR_POX IPR047210 Pyruvate oxidase POXB-like, pyrimidine-binding domain 4 169 6.55409E-83
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 364 565 4.29E-49
Gene3D G3DSA:3.40.50.1220 - - - 186 341 5.8E-34

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.