Pseudomonas mendocina NK-01, MDS_2415

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0003824	catalytic activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF02775	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0000287	magnesium ion binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00205	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0030976	thiamine pyrophosphate binding	ISM Inferred from Sequence Model Term mapped from: InterPro:PF02775	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pmk00620	Pyruvate metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF02776	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	IPR012001	Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain	4	173	4.7E-43
PANTHER	PTHR42981	PYRUVATE DEHYDROGENASE [UBIQUINONE]	IPR047211	Pyruvate oxidase/Pyruvate dehydrogenase [ubiquinone]-like	1	579	0.0
SUPERFAMILY	SSF52518	Thiamin diphosphate-binding fold (THDP-binding)	IPR029061	Thiamin diphosphate-binding fold	364	565	4.29E-49
CDD	cd02014	TPP_POX	IPR047212	Pyruvate oxidase POXB-like, PP-binding domain	365	551	9.84803E-79
SUPERFAMILY	SSF52518	Thiamin diphosphate-binding fold (THDP-binding)	IPR029061	Thiamin diphosphate-binding fold	2	175	5.89E-48
CDD	cd07039	TPP_PYR_POX	IPR047210	Pyruvate oxidase POXB-like, pyrimidine-binding domain	4	169	6.55409E-83
Gene3D	G3DSA:3.40.50.1220	-	-	-	186	341	5.8E-34
Gene3D	G3DSA:3.40.50.970	-	-	-	355	582	4.2E-47
SUPERFAMILY	SSF52467	DHS-like NAD/FAD-binding domain	IPR029035	DHS-like NAD/FAD-binding domain superfamily	189	356	2.91E-41
Pfam	PF00205	Thiamine pyrophosphate enzyme, central domain	IPR012000	Thiamine pyrophosphate enzyme, central domain	198	328	1.4E-26
Gene3D	G3DSA:3.40.50.970	-	-	-	1	176	2.2E-48
Pfam	PF02775	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	IPR011766	Thiamine pyrophosphate enzyme, TPP-binding	388	542	1.7E-23

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.