Pseudomonas mendocina NK-01, MDS_4407

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0051536 iron-sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00729
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004076 biotin synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01694
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009102 biotin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01694
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00729
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pmk00780 Biotin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc biotin biosynthesis from 8-amino-7-oxononanoate II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pmk01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF06968 Biotin and Thiamin Synthesis associated domain IPR010722 Biotin and thiamin synthesis-associated domain 226 316 1.3E-20
SMART SM00876 BATS_2 IPR010722 Biotin and thiamin synthesis-associated domain 226 318 2.3E-48
PIRSF PIRSF001619 Biotin_synth IPR024177 Biotin synthase 1 325 0.0
CDD cd01335 Radical_SAM - - 56 255 6.94928E-15
SMART SM00729 MiaB IPR006638 Elp3/MiaA/NifB-like, radical SAM core domain 49 261 8.7E-39
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 10 321 0.0
FunFam G3DSA:3.20.20.70:FF:000011 Biotin synthase - - 10 321 0.0
SFLD SFLDS00029 Radical SAM IPR007197 Radical SAM 5 325 0.0
PANTHER PTHR22976 BIOTIN SYNTHASE IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 5 333 0.0
SUPERFAMILY SSF102114 Radical SAM enzymes - - 11 320 1.44E-92
SFLD SFLDF00272 biotin synthase IPR024177 Biotin synthase 5 325 0.0
NCBIfam TIGR00433 JCVI: biotin synthase BioB IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 12 316 2.7E-125
Pfam PF04055 Radical SAM superfamily IPR007197 Radical SAM 56 208 2.8E-13
Hamap MF_01694 Biotin synthase [bioB]. IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 11 319 41.918339

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.