Pseudomonas sp. UW4, PputUW4_02535 (mexF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas sp. UW4
GCF_000316175.1|latest
Locus Tag
PputUW4_02535
Name
mexF
Replicon chromosome
Genomic location 2952740 - 2955919 (- strand)

Cross-References

RefSeq YP_007029535.1
GI 426409436
Entrez 14052245
NCBI Locus Tag PputUW4_02535

Product

Feature Type CDS
Coding Frame 1
Product Name
multidrug efflux RND transporter permease MexF
Synonyms
Evidence for Translation
Charge (pH 7) -6.67
Kyte-Doolittle Hydrophobicity Value 0.328
Molecular Weight (kDa) 114774.1
Isoelectric Point (pI) 5.93

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
adeF AdeF is the membrane fusion protein of the multidrug efflux complex AdeFGH. [PMID:20696879] ARO:3000777 protein homolog model Strict 1345.1 66.86 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 489 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000417 (2093 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PputUW4_02535
Search term: mexF

Human Homologs

References

No references are associated with this feature.