Pseudomonas protegens Pf-5, PFL_5382 (aroE)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0004764	shikimate 3-dehydrogenase (NADP+) activity	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_00222	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pfl01230	Biosynthesis of amino acids	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pfl01130	Biosynthesis of antibiotics	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pfl01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pfl01110	Biosynthesis of secondary metabolites	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pfl00400	Phenylalanine, tyrosine and tryptophan biosynthesis	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF08501	Shikimate dehydrogenase substrate binding domain	IPR013708	Shikimate dehydrogenase substrate binding, N-terminal	11	98	1.7E-20
Gene3D	G3DSA:3.40.50.10860	Leucine Dehydrogenase, chain A, domain 1	-	-	11	270	5.7E-77
SUPERFAMILY	SSF51735	NAD(P)-binding Rossmann-fold domains	IPR036291	NAD(P)-binding domain superfamily	111	281	2.02E-37
FunFam	G3DSA:3.40.50.720:FF:000086	Quinate/shikimate dehydrogenase	-	-	111	251	2.8E-42
SUPERFAMILY	SSF53223	Aminoacid dehydrogenase-like, N-terminal domain	IPR046346	Aminoacid dehydrogenase-like, N-terminal domain superfamily	5	110	1.61E-25
Pfam	PF18317	Shikimate 5'-dehydrogenase C-terminal domain	IPR041121	SDH, C-terminal	250	277	6.4E-6
Hamap	MF_00222	Shikimate dehydrogenase (NADP(+)) [aroE].	IPR022893	Shikimate dehydrogenase family	6	282	26.728407
CDD	cd01065	NAD_bind_Shikimate_DH	-	-	110	267	8.55622E-41
Gene3D	G3DSA:3.40.50.720	-	-	-	111	251	5.7E-77
Pfam	PF01488	Shikimate / quinate 5-dehydrogenase	IPR006151	Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase	123	199	2.1E-5
PANTHER	PTHR21089	SHIKIMATE DEHYDROGENASE	IPR022893	Shikimate dehydrogenase family	7	275	1.1E-57

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.