Pseudomonas denitrificans ATCC 13867, H681_07225 (metG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas denitrificans ATCC 13867
GCF_000349845.1|latest
Locus Tag
H681_07225
Name
metG
Replicon chromosome
Genomic location 1577602 - 1579638 (- strand)

Cross-References

RefSeq YP_007656861.1
GI 472324615
EC Number 6.1.1.10
Entrez 14995579
NCBI Locus Tag H681_07225

Product

Feature Type CDS
Coding Frame 1
Product Name
methionyl-tRNA ligase
Synonyms
Evidence for Translation
Charge (pH 7) -10.87
Kyte-Doolittle Hydrophobicity Value -0.222
Molecular Weight (kDa) 75247.9
Isoelectric Point (pI) 5.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7ULZ LIGASE 04/05/22 Crystal Structure of Methionine-tRNA ligase / Methionyl-tRNA synthetase (MetRS) from Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa 2.8 X-RAY DIFFRACTION 92.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002160 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: H681_07225
Search term: metG

Human Homologs

Ensembl 110, assembly GRCh38.p14
methionyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25133]
E-value: 7.3e-38
Percent Identity: 25.4

References

No references are associated with this feature.