Pseudomonas denitrificans ATCC 13867, H681_24815 (uvrD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016787 hydrolase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF13361
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR11070
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF13361
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003678 DNA helicase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR11070
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pdr03420 Nucleotide excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pdr03430 Mismatch repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:1.10.10.160 - IPR013986 DExx box DNA helicase domain superfamily 116 189 2.8E-101
Gene3D G3DSA:1.10.486.10 PCRA; domain 4 - - 385 540 0.0
Pfam PF13361 UvrD-like helicase C-terminal domain IPR014017 UvrD-like DNA helicase, C-terminal 279 618 5.3E-76
PANTHER PTHR11070 UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER IPR000212 DNA helicase, UvrD/REP type 10 642 0.0
CDD cd18807 SF1_C_UvrD - - 287 616 4.87225E-31
FunFam G3DSA:1.10.10.160:FF:000002 DNA helicase - - 116 189 2.0E-28
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 12 275 2.8E-101
Pfam PF00580 UvrD/REP helicase N-terminal domain IPR014016 UvrD-like helicase, ATP-binding domain 12 274 8.2E-72
FunFam G3DSA:3.40.50.300:FF:001201 ATP-dependent DNA helicase UvrD2 - - 282 386 4.1E-33
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 9 644 0.0
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 283 638 0.0
CDD cd17932 DEXQc_UvrD - - 16 285 4.45781E-85
FunFam G3DSA:1.10.486.10:FF:000003 ATP-dependent DNA helicase - - 385 550 1.2E-41

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.