Pseudomonas aeruginosa LESB58, PALES_49991 (mscL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008381 mechanosensitive ion channel activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00115
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00115
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0034220 ion transmembrane transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00115
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Membrane proteins Other LESB58 genes in this class
Adaptation, Protection Other LESB58 genes in this class
Transport of small molecules Other LESB58 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR30266 MECHANOSENSITIVE CHANNEL MSCL IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L 3 136 1.3E-38
Gene3D G3DSA:1.10.1200.120 - IPR036019 Large-conductance mechanosensitive channel MscL 3 134 1.3E-41
SUPERFAMILY SSF81330 Gated mechanosensitive channel IPR036019 Large-conductance mechanosensitive channel MscL 13 127 1.7E-35
Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. IPR001185 Large-conductance mechanosensitive channel 3 132 24.314693
PRINTS PR01264 Bacterial mechano-sensitive ion channel signature IPR001185 Large-conductance mechanosensitive channel 93 102 9.2E-13
NCBIfam TIGR00220 JCVI: large conductance mechanosensitive channel protein MscL IPR001185 Large-conductance mechanosensitive channel 4 133 2.1E-47
FunFam G3DSA:1.10.1200.120:FF:000001 Large-conductance mechanosensitive channel - - 3 134 2.3E-65
PRINTS PR01264 Bacterial mechano-sensitive ion channel signature IPR001185 Large-conductance mechanosensitive channel 6 20 9.2E-13
Pfam PF01741 Large-conductance mechanosensitive channel, MscL IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L 3 131 9.8E-45
PRINTS PR01264 Bacterial mechano-sensitive ion channel signature IPR001185 Large-conductance mechanosensitive channel 84 92 9.2E-13

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.