Pseudomonas aeruginosa 2192, PA2G_03794

Gene Feature Overview

Strain	Pseudomonas aeruginosa 2192 GCF_000152545.1|latest
Locus Tag	PA2G_03794
Name
Replicon	chromosome
Genomic location	4252071 - 4252985 (- strand)

Cross-References

RefSeq	ZP_04936328.1
GI	254243006
NCBI Locus Tag	PA2G_03794
UniProtKB Acc	A3LG66
UniProtKB ID	A3LG66_PSEAE

Product

Feature Type	CDS
Coding Frame	1
Product Name	NAD-dependent dehydratase
Synonyms
Evidence for Translation
Charge (pH 7)	-1.65
Kyte-Doolittle Hydrophobicity Value	-0.149
Molecular Weight (kDa)	33.9
Isoelectric Point (pI)	6.68

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
6X3B	OXIDOREDUCTASE	05/21/20	Structure of RMD from Pseudomonas aeruginosa complexed with NADPH	Pseudomonas aeruginosa	1.91	X-RAY DIFFRACTION	99.3

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG005000 (385 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA2G_03794 Search term: NAD-dependent dehydratase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000370194 GDP-mannose 4,6-dehydratase [Source:HGNC Symbol;Acc:HGNC:4369] E-value: 5.6e-14 Percent Identity: 27.4
Ensembl 110, assembly GRCh38.p14	ENSP00000436726 GDP-mannose 4,6-dehydratase [Source:HGNC Symbol;Acc:HGNC:4369] E-value: 5.6e-14 Percent Identity: 27.4

References