Pseudomonas aeruginosa 2192, PA2G_04380
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Cellular Component | GO:0016021 | integral component of membrane |
Inferred from Sequence Model
Term mapped from: InterPro:SM00304
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0000155 | phosphorelay sensor kinase activity |
Inferred from Sequence Model
Term mapped from: InterPro:SSF47384
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0007165 | signal transduction |
Inferred from Sequence Model
Term mapped from: InterPro:SSF47384
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
|
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Coils | Coil | Coil | - | - | 301 | 321 | - |
| SUPERFAMILY | SSF103190 | Sensory domain-like | IPR029151 | Periplasmic sensor-like domain superfamily | 79 | 179 | 2.86E-12 |
| PANTHER | PTHR45436 | SENSOR HISTIDINE KINASE YKOH | - | - | 1 | 473 | 0.0 |
| CDD | cd00082 | HisKA | IPR003661 | Signal transduction histidine kinase, dimerisation/phosphoacceptor domain | 257 | 316 | 8.33658E-12 |
| Gene3D | G3DSA:1.10.287.130 | - | - | - | 256 | 317 | 3.6E-13 |
| Pfam | PF00672 | HAMP domain | IPR003660 | HAMP domain | 201 | 251 | 1.5E-7 |
| Pfam | PF00512 | His Kinase A (phospho-acceptor) domain | IPR003661 | Signal transduction histidine kinase, dimerisation/phosphoacceptor domain | 258 | 319 | 1.3E-12 |
| SUPERFAMILY | SSF47384 | Homodimeric domain of signal transducing histidine kinase | IPR036097 | Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily | 241 | 319 | 2.75E-13 |
| Gene3D | G3DSA:3.30.565.10 | - | IPR036890 | Histidine kinase/HSP90-like ATPase superfamily | 318 | 473 | 2.8E-25 |
| CDD | cd06225 | HAMP | - | - | 210 | 250 | 3.29604E-5 |
| Gene3D | G3DSA:6.10.340.10 | - | - | - | 168 | 255 | 2.2E-9 |
| PANTHER | PTHR45436:SF10 | TWO-COMPONENT SYSTEM SENSOR PROTEIN | - | - | 1 | 473 | 0.0 |
| CDD | cd18773 | PDC1_HK_sensor | - | - | 40 | 167 | 2.17824E-4 |
| Gene3D | G3DSA:3.30.450.20 | PAS domain | - | - | 68 | 167 | 1.7E-7 |
| SMART | SM00387 | HKATPase_4 | IPR003594 | Histidine kinase/HSP90-like ATPase | 365 | 474 | 2.7E-16 |
| CDD | cd16945 | HATPase_CreC-like | - | - | 366 | 471 | 3.1924E-59 |
| Pfam | PF02518 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase | IPR003594 | Histidine kinase/HSP90-like ATPase | 369 | 468 | 1.5E-10 |
| SMART | SM00304 | HAMP_11 | IPR003660 | HAMP domain | 204 | 255 | 3.5E-5 |
| SMART | SM00388 | HisKA_10 | IPR003661 | Signal transduction histidine kinase, dimerisation/phosphoacceptor domain | 255 | 320 | 3.4E-16 |
| SUPERFAMILY | SSF55874 | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | IPR036890 | Histidine kinase/HSP90-like ATPase superfamily | 310 | 473 | 9.95E-29 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.