Pseudomonas aeruginosa PACS2, A0K_RS00910

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006935 chemotaxis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50341
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.287.560
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00073
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50341
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.30.565.10:FF:000016 Chemotaxis protein CheA, putative - - 309 492 2.6E-73
FunFam G3DSA:2.30.30.40:FF:000048 Chemotaxis protein CheA, putative - - 564 625 8.2E-27
Coils Coil Coil - - 284 304 -
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 355 492 4.9E-16
CDD cd00731 CheA_reg - - 493 625 1.85414E-44
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 309 492 4.5E-55
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 5 102 5.6E-30
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 7 105 1.0E-21
Pfam PF01584 CheW-like domain IPR002545 CheW-like domain 498 625 1.7E-26
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 437 447 1.1E-12
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 477 490 1.1E-12
Gene3D G3DSA:2.30.30.40 SH3 Domains - - 565 625 1.8E-24
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 310 491 3.8E-37
PANTHER PTHR43395 SENSOR HISTIDINE KINASE CHEA - - 1 632 0.0
Gene3D G3DSA:1.10.287.560 - IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily 246 308 1.3E-21
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 353 493 1.2E-25
Pfam PF02895 Signal transducing histidine kinase, homodimeric domain IPR004105 Histidine kinase CheA-like, homodimeric domain 247 308 8.6E-18
SMART SM01231 H_kinase_dim_2 IPR004105 Histidine kinase CheA-like, homodimeric domain 245 308 1.5E-23
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 4 127 1.57E-33
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 453 471 1.1E-12
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 247 309 1.26E-15
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 398 412 1.1E-12
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 2 138 6.3E-36
SMART SM00260 chew_2 IPR002545 CheW-like domain 485 626 4.6E-34
CDD cd16916 HATPase_CheA-like - - 316 490 2.07097E-97
SUPERFAMILY SSF50341 CheW-like IPR036061 CheW-like domain superfamily 492 625 1.57E-30
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 5 103 7.47526E-22

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.