Pseudomonas aeruginosa PACS2, A0K_RS27335 (aceE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000156
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF52922
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Energy metabolism Other PACS2 genes in this class
Amino acid biosynthesis and metabolism Other PACS2 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
NCBIfam TIGR00759 JCVI: pyruvate dehydrogenase (acetyl-transferring), homodimeric type IPR004660 Pyruvate dehydrogenase E1 component 2 880 0.0
Gene3D G3DSA:3.40.50.920 - IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II 699 881 2.7E-83
Pfam PF00456 Transketolase, thiamine diphosphate binding domain IPR005474 Transketolase, N-terminal 123 287 4.6E-8
Gene3D G3DSA:3.40.50.970 - - - 51 464 0.0
FunFam G3DSA:3.40.50.970:FF:000011 Pyruvate dehydrogenase E1 component - - 51 464 0.0
Coils Coil Coil - - 880 882 -
SUPERFAMILY SSF52922 TK C-terminal domain-like IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II 694 880 1.17E-63
Gene3D G3DSA:3.40.50.970 - - - 465 698 1.4E-113
Pfam PF17831 Pyruvate dehydrogenase E1 component middle domain IPR041621 Pyruvate dehydrogenase E1 component, middle domain 473 692 4.2E-117
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 52 460 0.0
PIRSF PIRSF000156 Pyruvate_dh_E1 IPR004660 Pyruvate dehydrogenase E1 component 1 882 0.0
SUPERFAMILY SSF52518 Thiamin diphosphate-binding fold (THDP-binding) IPR029061 Thiamin diphosphate-binding fold 466 693 2.94E-97
PANTHER PTHR43825 PYRUVATE DEHYDROGENASE E1 COMPONENT - - 62 856 0.0
CDD cd02017 TPP_E1_EcPDC_like IPR035807 Pyruvate dehydrogenase E1 component, N-terminal 70 454 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.