Pseudomonas aeruginosa PACS2, A0K_RS27340

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0045254 pyruvate dehydrogenase complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006096 glycolytic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016746 transferase activity, transferring acyl groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF47005
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004742 dihydrolipoyllysine-residue acetyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other PACS2 genes in this class
Energy metabolism Other PACS2 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd06849 lipoyl_domain - - 120 192 2.19733E-19
FunFam G3DSA:2.40.50.100:FF:000009 Acetyltransferase component of pyruvate dehydrogenase complex - - 1 80 1.7E-30
SUPERFAMILY SSF52777 CoA-dependent acyltransferases - - 306 547 1.25E-79
Gene3D G3DSA:4.10.320.10 - IPR036625 E3-binding domain superfamily 247 292 4.7E-17
SUPERFAMILY SSF47005 Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex IPR036625 E3-binding domain superfamily 242 286 4.97E-12
FunFam G3DSA:4.10.320.10:FF:000003 Acetyltransferase component of pyruvate dehydrogenase complex - - 247 292 9.5E-24
Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain 318 546 1.9E-76
CDD cd06849 lipoyl_domain - - 5 74 3.27932E-22
FunFam G3DSA:3.30.559.10:FF:000004 Acetyltransferase component of pyruvate dehydrogenase complex - - 302 547 1.3E-119
Gene3D G3DSA:2.40.50.100 - - - 2 79 3.7E-25
Gene3D G3DSA:3.30.559.10 - IPR023213 Chloramphenicol acetyltransferase-like domain superfamily 305 547 5.7E-87
Gene3D G3DSA:2.40.50.100 - - - 120 198 2.0E-22
SUPERFAMILY SSF51230 Single hybrid motif IPR011053 Single hybrid motif 118 212 6.41E-23
MobiDBLite mobidb-lite consensus disorder prediction - - 75 117 -
Pfam PF02817 e3 binding domain IPR004167 Peripheral subunit-binding domain 247 282 8.2E-15
Pfam PF00364 Biotin-requiring enzyme IPR000089 Biotin/lipoyl attachment 121 192 4.7E-23
MobiDBLite mobidb-lite consensus disorder prediction - - 202 248 -
Pfam PF00364 Biotin-requiring enzyme IPR000089 Biotin/lipoyl attachment 5 74 9.9E-23
FunFam G3DSA:2.40.50.100:FF:000009 Acetyltransferase component of pyruvate dehydrogenase complex - - 118 198 5.6E-30
PANTHER PTHR43178 DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX - - 5 108 0.0
Coils Coil Coil - - 433 453 -
SUPERFAMILY SSF51230 Single hybrid motif IPR011053 Single hybrid motif 4 93 4.06E-23
NCBIfam TIGR01348 JCVI: dihydrolipoyllysine-residue acetyltransferase IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex 4 547 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.