Pseudomonas aeruginosa PAO1, PA0153 (pcaH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0153
Name
pcaH
Replicon chromosome
Genomic location 174773 - 175492 (+ strand)
Transposon Mutants 6 transposon mutants in PAO1

Cross-References

RefSeq NP_248843.1
GI 15595351
Affymetrix PA0153_pcaH_at
Entrez 878130
GenBank AAG03543.1
INSDC AAG03543.1
NCBI Locus Tag PA0153
protein_id(GenBank) gb|AAG03543.1|AE004453_6|gnl|PseudoCAP|PA0153
TIGR NTL03PA00154
UniParc UPI00000C4F68
UniProtKB Acc Q9I6X9
UniProtKB ID Q9I6X9_PSEAE
UniRef100 UniRef100_W0YJK9
UniRef50 UniRef50_P00437
UniRef90 UniRef90_A6UXU2

Product

Feature Type CDS
Coding Frame 1
Product Name
protocatechuate 3,4-dioxygenase, beta subunit
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 6.33
Kyte-Doolittle Hydrophobicity Value -0.548
Molecular Weight (kDa) 27.1
Isoelectric Point (pI) 9.30

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 129 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000151 (503 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0153
Search term: pcaH

Human Homologs

References

Structure and assembly of protocatechuate 3,4-dioxygenase.
Ohlendorf DH, Lipscomb JD, Weber PC
Nature 1988 Nov 24;336(6197):403-5
PubMed ID: 3194022