Pseudomonas aeruginosa PAO1, PA0448 (gcdR)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA0448
|
| Name |
gcdR
|
| Replicon | chromosome |
| Genomic location | 504121 - 505029 (+ strand) |
| Transposon Mutants | 2 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
Cross-References
| RefSeq | NP_249139.1 |
| GI | 15595645 |
| Affymetrix | PA0448_at |
| Entrez | 881014 |
| GenBank | AAG03837.1 |
| INSDC | AAG03837.1 |
| NCBI Locus Tag | PA0448 |
| protein_id(GenBank) | gb|AAG03837.1|AE004482_4|gnl|PseudoCAP|PA0448 |
| TIGR | NTL03PA00449 |
| UniParc | UPI00000C505E |
| UniProtKB Acc | Q9I670 |
| UniProtKB ID | Q9I670_PSEAE |
| UniRef100 | UniRef100_A0A081HDG5 |
| UniRef50 | UniRef50_Q4KKG5 |
| UniRef90 | UniRef90_W0YLS5 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
transcriptional regulator, GcdR
|
| Synonyms |
probable transcriptional regulator |
| Evidence for Translation | |
| Charge (pH 7) | 1.87 |
| Kyte-Doolittle Hydrophobicity Value | -0.153 |
| Molecular Weight (kDa) | 34.0 |
| Isoelectric Point (pI) | 7.73 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 494 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG000439 (1047 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA0448
Search term: gcdR
Search term: transcriptional regulator, GcdR
|
Human Homologs
References
|
Molecular characterization of lysR-lysXE, gcdR-gcdHG and amaR-amaAB operons for lysine export and catabolism: a comprehensive lysine catabolic network in Pseudomonas aeruginosa PAO1.
Madhuri Indurthi S, Chou HT, Lu CD
Microbiology (Reading, Engl.) 2016 May;162(5):876-88
PubMed ID: 26967762
|