Pseudomonas aeruginosa PAO1, PA1057 (shaD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1057
Name
shaD
Synonym: phaE
Replicon chromosome
Genomic location 1146693 - 1147217 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249748.1
GI 15596254
Affymetrix PA1057_at
DNASU PaCD00006484
Entrez 881110
GenBank AAG04446.1
INSDC AAG04446.1
NCBI Locus Tag PA1057
protein_id(GenBank) gb|AAG04446.1|AE004537_11|gnl|PseudoCAP|PA1057
TIGR NTL03PA01058
UniParc UPI00000C522B
UniProtKB Acc Q9I4R7
UniProtKB ID Q9I4R7_PSEAE
UniRef100 UniRef100_Q9I4R7
UniRef50 UniRef50_Q02IM4
UniRef90 UniRef90_Q02IM4

Product

Feature Type CDS
Coding Frame 1
Product Name
ShaD
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.11
Kyte-Doolittle Hydrophobicity Value 0.752
Molecular Weight (kDa) 19.3
Isoelectric Point (pI) 6.94

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 212 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001019 (421 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1057
Search term: shaD
Search term: ShaD

Human Homologs

References

Characterization of a multigene-encoded sodium/hydrogen antiporter (sha) from Pseudomonas aeruginosa: its involvement in pathogenesis.
Kosono S, Haga K, Tomizawa R, Kajiyama Y, Hatano K, Takeda S, Wakai Y, Hino M, Kudo T
J Bacteriol 2005 Aug;187(15):5242-8
PubMed ID: 16030218