Pseudomonas aeruginosa PAO1, PA1079 (flgD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1079
Name
flgD
Replicon chromosome
Genomic location 1165141 - 1165854 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249770.1
GI 15596276
Affymetrix PA1079_flgD_at
DNASU PaCD00006497
Entrez 878124
GenBank AAG04468.1
INSDC AAG04468.1
NCBI Locus Tag PA1079
protein_id(GenBank) gb|AAG04468.1|AE004539_10|gnl|PseudoCAP|PA1079
TIGR NTL03PA01080
UniParc UPI00000C523C
UniProtKB Acc Q9I4Q0
UniProtKB ID Q9I4Q0_PSEAE
UniRef100 UniRef100_W0YPY7
UniRef50 UniRef50_Q4K867
UniRef90 UniRef90_Q02IP6

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellar basal-body rod modification protein FlgD
Product Name Confidence: Class 2
Synonyms flagellar hook cap (scaffold)
Evidence for Translation
Charge (pH 7) -1.01
Kyte-Doolittle Hydrophobicity Value -0.244
Molecular Weight (kDa) 24.9
Isoelectric Point (pI) 5.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Fimbrial
Note: This is based on PSORTb V3.0 secondary localization prediction
 Class 3
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3OSV STRUCTURAL PROTEIN 09/10/10 The crytsal structure of FLGD from P. Aeruginosa Pseudomonas aeruginosa 2.35 X-RAY DIFFRACTION 100.0

Virulence Evidence

Source 1
Database VFDB : VF0273
Category Flagella
Evidence
Host Organism
Notes
Reference 14617143

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 296 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001041 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1079
Search term: flgD

Human Homologs

References

FlgD is a scaffolding protein needed for flagellar hook assembly in Salmonella typhimurium.
Ohnishi K, Ohto Y, Aizawa S, Macnab RM, Iino T
J Bacteriol 1994 Apr;176(8):2272-81
PubMed ID: 8157595
Nucleotide sequence of the flgD gene of Salmonella typhimurium which is essential for flagellar hook formation.
Kutsukake K, Doi H
Biochim Biophys Acta 1994 Aug 2;1218(3):443-6
PubMed ID: 8049271