Pseudomonas aeruginosa PAO1, PA1151 (imm2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1151
Name
imm2
Replicon chromosome
Genomic location 1245665 - 1245928 (+ strand)

Cross-References

RefSeq NP_249842.1
GI 15596348
Affymetrix PA1151_imm2_at
Entrez 879819
GenBank AAG04540.1
INSDC AAG04540.1
NCBI Locus Tag PA1151
protein_id(GenBank) gb|AAG04540.1|AE004545_3|gnl|PseudoCAP|PA1151
TIGR NTL03PA01152
UniParc UPI000012D624
UniProtKB Acc Q06579
UniProtKB ID IMM2_PSEAE
UniRef100 UniRef100_Q06579
UniRef50 UniRef50_Q06579
UniRef90 UniRef90_Q06579

Product

Feature Type CDS
Coding Frame 1
Product Name
pyocin S2 immunity protein
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 0.47
Kyte-Doolittle Hydrophobicity Value -0.922
Molecular Weight (kDa) 10.0
Isoelectric Point (pI) 7.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4QKO ANTIMICROBIAL PROTEIN 06/07/14 The Crystal Structure of the Pyocin S2 Nuclease Domain, Immunity Protein Complex at 1.8 Angstroms Pseudomonas aeruginosa 1.8 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 16 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001110 (184 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1151
Search term: imm2

Human Homologs

References

Purification of the pyocin S2 complex from Pseudomonas aeruginosa PAO1: analysis of DNase activity.
Seo Y, Galloway DR
Biochem Biophys Res Commun 1990 Oct 30;172(2):455-61
PubMed ID: 2122894
Molecular structures and functions of pyocins S1 and S2 in Pseudomonas aeruginosa.
Sano Y, Matsui H, Kobayashi M, Kageyama M
J Bacteriol 1993 May;175(10):2907-16
PubMed ID: 8491711