Pseudomonas aeruginosa PAO1, PA1227

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1227
Name
Replicon chromosome
Genomic location 1329192 - 1330040 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249918.1
GI 15596424
Affymetrix PA1227_at
Entrez 882189
GenBank AAG04616.1
NCBI Locus Tag PA1227
protein_id(GenBank) gb|AAG04616.1|AE004552_6|gnl|PseudoCAP|PA1227
TIGR NTL03PA01228
UniProtKB Acc Q9I4B1
UniProtKB ID Q9I4B1_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.34
Kyte-Doolittle Hydrophobicity Value -0.045
Molecular Weight (kDa) 30.9
Isoelectric Point (pI) 6.90

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 11 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001180 (298 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1227

Human Homologs

References

A novel gentamicin resistance gene in Enterococcus.
Chow JW, Zervos MJ, Lerner SA, Thal LA, Donabedian SM, Jaworski DD, Tsai S, Shaw KJ, Clewell DB
Antimicrob Agents Chemother 1997 Mar;41(3):511-4
PubMed ID: 9055984