Pseudomonas aeruginosa PAO1, PA1379

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest
Locus Tag
PA1379
Name
Replicon chromosome
Genomic location 1496087 - 1496920 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250070.1
GI 15596576
Affymetrix PA1379_at
DNASU PaCD00006636
Entrez 881131
GenBank AAG04768.1
INSDC AAG04768.1
NCBI Locus Tag PA1379
protein_id(GenBank) gb|AAG04768.1|AE004567_7|gnl|PseudoCAP|PA1379
TIGR NTL03PA01380
UniParc UPI00000C5349
UniProtKB Acc Q9I3W5
UniProtKB ID Q9I3W5_PSEAE
UniRef100 UniRef100_W1MLB1
UniRef50 UniRef50_A9ALU7
UniRef90 UniRef90_W1MLB1

Product

Feature Type CDS
Coding Frame 1
Product Name
probable short-chain dehydrogenase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -1.06
Kyte-Doolittle Hydrophobicity Value -0.079
Molecular Weight (kDa) 29.7
Isoelectric Point (pI) 6.54

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown (This protein may have multiple localization sites) Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold Protein Structure Database

Available for P. aeruginosa PAO1.

View predicted 3D structure in AlphaFold DB

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 652 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001308 (602 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1379

Human Homologs

Ensembl 107, assembly GRCh38.p13
retinol dehydrogenase 8 [Source:NCBI gene;Acc:50700]
E-value: 1.5e-26
Percent Identity: 34.6
Ensembl 107, assembly GRCh38.p13
retinol dehydrogenase 8 [Source:NCBI gene;Acc:50700]
E-value: 1.5e-26
Percent Identity: 34.6

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295