Pseudomonas aeruginosa PAO1, PA1661 (hsiH2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1661
Name
hsiH2
Replicon chromosome
Genomic location 1809737 - 1810744 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250352.1
GI 15596858
Affymetrix PA1661_at
DNASU PaCD00006752
Entrez 880788
GenBank AAG05050.1
INSDC AAG05050.1
NCBI Locus Tag PA1661
protein_id(GenBank) gb|AAG05050.1|AE004594_2|gnl|PseudoCAP|PA1661
TIGR NTL03PA01662
UniParc UPI00000C5433
UniProtKB Acc Q9I364
UniProtKB ID Q9I364_PSEAE
UniRef100 UniRef100_Q9I364
UniRef50 UniRef50_G8Q742
UniRef90 UniRef90_W0YRS5

Product

Feature Type CDS
Coding Frame 1
Product Name
HsiH2
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 5.56
Kyte-Doolittle Hydrophobicity Value -0.249
Molecular Weight (kDa) 38.5
Isoelectric Point (pI) 8.77

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database PseudoCAP
Category Hcp secretion island-2 encoded type VI secretion system (H2-T6SS)
Evidence ECO:0000317
genomic context evidence used in manual assertion
Host Organism Homo sapiens
Notes H2-T6SS rendered inactive via clpV2 deletion.
Reference 22665491

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 102 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000088 (1157 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1661
Search term: hsiH2
Search term: HsiH2

Human Homologs

References

No references are associated with this feature.