Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1662
|
Name |
clpV2
|
Replicon | chromosome |
Genomic location | 1810751 - 1813384 (+ strand) |
Transposon Mutants | 2 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 3 transposon mutants in orthologs |
RefSeq | NP_250353.1 |
GI | 15596859 |
Affymetrix | PA1662_at |
Entrez | 878010 |
GenBank | AAG05051.1 |
NCBI Locus Tag | PA1662 |
protein_id(GenBank) | gb|AAG05051.1|AE004594_3|gnl|PseudoCAP|PA1662 |
TIGR | NTL03PA01663 |
UniProtKB Acc | Q9I363 |
UniProtKB ID | Q9I363_PSEAE |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
clpV2
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -16.79 |
Kyte-Doolittle Hydrophobicity Value | -0.201 |
Molecular Weight (kDa) | 95.8 |
Isoelectric Point (pI) | 5.47 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | PseudoCAP |
Category | Hcp secretion island-2 encoded type VI secretion system (H2-T6SS) |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Caenorhabditis elegans |
Notes | clpV2 mutant significantly less virulent than WT PAO1 strain in C elegans slow killing assay |
Reference | 22665491 |
Source 2 | |
Database | PseudoCAP |
Category | Hcp secretion island-2 encoded type VI secretion system (H2-T6SS) |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Homo sapiens |
Notes | Infection of Calu-3 cells with PAO1 clpV2 mutant resulted in 50% decrease in Akt phosphorylation levels |
Reference | 22665491 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 597 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000089 (1168 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1662
Search term: clpV2
Search term: clpV2
|
The heat shock protein ClpB mediates the development of thermotolerance in the cyanobacterium Synechococcus sp. strain PCC 7942.
Eriksson MJ, Clarke AK
J Bacteriol 1996 Aug;178(16):4839-46
PubMed ID: 8759846
|