Pseudomonas aeruginosa PAO1, PA1773 (cmaX)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1773
Name
cmaX
Replicon chromosome
Genomic location 1918275 - 1919273 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_250464.1
GI 15596970
Affymetrix PA1773_at
Entrez 880766
GenBank AAG05162.1
INSDC AAG05162.1
NCBI Locus Tag PA1773
protein_id(GenBank) gb|AAG05162.1|AE004603_2|gnl|PseudoCAP|PA1773
TIGR NTL03PA01774
UniParc UPI00000D4237
UniProtKB Acc G3XD00
UniProtKB ID G3XD00_PSEAE
UniRef100 UniRef100_W0YP08
UniRef50 UniRef50_Q88L50
UniRef90 UniRef90_W0YP08

Product

Feature Type CDS
Coding Frame 1
Product Name
CmaX protein
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.08
Kyte-Doolittle Hydrophobicity Value -0.163
Molecular Weight (kDa) 37.8
Isoelectric Point (pI) 5.05

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7NH9 TRANSPORT PROTEIN 02/10/21 structure of the full-length CmaX protein Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 3.03 ELECTRON MICROSCOPY 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 374 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003622 (530 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1773
Search term: cmaX
Search term: CmaX protein

Human Homologs

References

Influence of a putative ECF sigma factor on expression of the major outer membrane protein, OprF, in Pseudomonas aeruginosa and Pseudomonas fluorescens.
Brinkman FS, Schoofs G, Hancock RE, De Mot R
J Bacteriol 1999 Aug;181(16):4746-54
PubMed ID: 10438740
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295