Pseudomonas aeruginosa PAO1, PA1983 (exaB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1983
Name
exaB
Replicon chromosome
Genomic location 2169464 - 2169901 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_250673.1
GI 15597179
Affymetrix PA1983_exaB_at
Entrez 880387
GenBank AAG05371.1
INSDC AAG05371.1
NCBI Locus Tag PA1983
protein_id(GenBank) gb|AAG05371.1|AE004625_1|gnl|PseudoCAP|PA1983
TIGR NTL03PA01983
UniParc UPI00000C5540
UniProtKB Acc Q9I2C5
UniProtKB ID Q9I2C5_PSEAE
UniRef100 UniRef100_Q9I2C5
UniRef50 UniRef50_Q9I2C5
UniRef90 UniRef90_Q9I2C5

Product

Feature Type CDS
Coding Frame 1
Product Name
cytochrome c550
Product Name Confidence: Class 1
Synonyms cytochrome c(EDH)
Evidence for Translation
Charge (pH 7) -3.11
Kyte-Doolittle Hydrophobicity Value -0.306
Molecular Weight (kDa) 15.8
Isoelectric Point (pI) 5.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 37 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003449 (422 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1983
Search term: exaB
Search term: cytochrome c550

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Quaternary structure of quinoprotein ethanol dehydrogenase from Pseudomonas aeruginosa and its reoxidation with a novel cytochrome c from this organism.
Schrover JM, Frank J, van Wielink JE, Duine JA
Biochem J 1993 Feb 15;290 ( Pt 1)(Pt 1):123-7
PubMed ID: 8382472
Cytochrome c550 is an essential component of the quinoprotein ethanol oxidation system in Pseudomonas aeruginosa: cloning and sequencing of the genes encoding cytochrome c550 and an adjacent acetaldehyde dehydrogenase.
Schobert M, Görisch H
Microbiology (Reading) 1999 Feb;145 ( Pt 2):471-481
PubMed ID: 10075429