Pseudomonas aeruginosa PAO1, PA2537

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2537
Name
Replicon chromosome
Genomic location 2865107 - 2865736 (- strand)

Cross-References

RefSeq NP_251227.1
GI 15597733
Affymetrix PA2537_at
Entrez 878085
GenBank AAG05925.1
INSDC AAG05925.1
NCBI Locus Tag PA2537
protein_id(GenBank) gb|AAG05925.1|AE004681_7|gnl|PseudoCAP|PA2537
TIGR NTL03PA02537
UniParc UPI00000C5726
UniProtKB Acc Q9I0U7
UniProtKB ID Q9I0U7_PSEAE
UniRef100 UniRef100_A0A072ZQR1
UniRef50 UniRef50_S9QJT5
UniRef90 UniRef90_Q02MY6

Product

Feature Type CDS
Coding Frame 1
Product Name
probable acyltransferase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (23.15 kDa, PMID:21751344)
Charge (pH 7) 0.93
Kyte-Doolittle Hydrophobicity Value -0.044
Molecular Weight (kDa) 23.1
Isoelectric Point (pI) 7.66

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Vesicle Class 1
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 175 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003032 (433 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2537

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Cloning of a coconut endosperm cDNA encoding a 1-acyl-sn-glycerol-3-phosphate acyltransferase that accepts medium-chain-length substrates.
Knutzon DS, Lardizabal KD, Nelsen JS, Bleibaum JL, Davies HM, Metz JG
Plant Physiol 1995 Nov;109(3):999-1006
PubMed ID: 8552723
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344