Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA2612
|
Name |
serS
|
Replicon | chromosome |
Genomic location | 2953416 - 2954696 (- strand) |
RefSeq | NP_251302.1 |
GI | 15597808 |
Affymetrix | PA2612_serS_at |
Entrez | 882318 |
GenBank | AAG06000.1 |
INSDC | AAG06000.1 |
NCBI Locus Tag | PA2612 |
protein_id(GenBank) | gb|AAG06000.1|AE004689_12|gnl|PseudoCAP|PA2612 |
TIGR | NTL03PA02612 |
UniParc | UPI00000C5769 |
UniProtKB Acc | Q9I0M6 |
UniProtKB ID | SYS_PSEAE |
UniRef100 | UniRef100_B7UW10 |
UniRef50 | UniRef50_Q6F8G5 |
UniRef90 | UniRef90_A4VLU7 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
seryl-tRNA synthetase
|
Synonyms | |
Evidence for Translation |
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -9.93 |
Kyte-Doolittle Hydrophobicity Value | -0.356 |
Molecular Weight (kDa) | 47.2 |
Isoelectric Point (pI) | 5.25 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
6HE3 | LIGASE | 08/20/18 | Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)cytidine | Pseudomonas aeruginosa | 2.16 | X-RAY DIFFRACTION | 99.8 |
6HE1 | LIGASE | 08/20/18 | Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-sulfamoyl)N3-methyluridine | Pseudomonas aeruginosa | 2.22 | X-RAY DIFFRACTION | 99.8 |
6HDZ | LIGASE | 08/20/18 | Pseudomonas aeruginosa Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-Sulfamoyl)uridine | Pseudomonas aeruginosa | 2.06 | X-RAY DIFFRACTION | 99.8 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 651 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG002939 (536 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA2612
Search term: serS
Search term: seryl-tRNA synthetase
|
Ensembl
110, assembly
GRCh38.p14
|
seryl-tRNA synthetase 1 [Source:HGNC Symbol;Acc:HGNC:10537]
E-value:
1.5e-52
Percent Identity:
32.2
|
A second class of synthetase structure revealed by X-ray analysis of Escherichia coli seryl-tRNA synthetase at 2.5 A.
Cusack S, Berthet-Colominas C, Härtlein M, Nassar N, Leberman R
Nature 1990 Sep 20;347(6290):249-55
PubMed ID: 2205803
|
Seryl-tRNA synthetase from Escherichia coli: functional evidence for cross-dimer tRNA binding during aminoacylation.
Vincent C, Borel F, Willison JC, Leberman R, Härtlein M
Nucleic Acids Res 1995 Apr 11;23(7):1113-8
PubMed ID: 7537870
|
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
|