Pseudomonas aeruginosa PAO1, PA3102 (xcpS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3102
Name
xcpS
Replicon chromosome
Genomic location 3480697 - 3481914 (- strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_251792.1
GI 15598298
Affymetrix PA3102_xcpS_at
Entrez 878732
GenBank AAG06490.1
INSDC AAG06490.1
NCBI Locus Tag PA3102
protein_id(GenBank) gb|AAG06490.1|AE004734_8|gnl|PseudoCAP|PA3102
TIGR NTL03PA03102
UniParc UPI000012BC3A
UniProtKB Acc Q00513
UniProtKB ID GSPF_PSEAE
UniRef100 UniRef100_Q00513
UniRef50 UniRef50_Q00513
UniRef90 UniRef90_Q00513

Product

Feature Type CDS
Coding Frame 1
Product Name
general secretion pathway protein F
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 11.21
Kyte-Doolittle Hydrophobicity Value 0.312
Molecular Weight (kDa) 44.1
Isoelectric Point (pI) 10.71

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 405 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000666 (814 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3102
Search term: xcpS

Human Homologs

References

Subcomplexes from the Xcp secretion system of Pseudomonas aeruginosa.
Robert V, Filloux A, Michel GP
FEMS Microbiol Lett 2005 Nov 1;252(1):43-50
PubMed ID: 16168578
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Protein secretion in Pseudomonas aeruginosa: characterization of seven xcp genes and processing of secretory apparatus components by prepilin peptidase.
Bally M, Filloux A, Akrim M, Ball G, Lazdunski A, Tommassen J
Mol Microbiol 1992 May;6(9):1121-31
PubMed ID: 1588814