Pseudomonas aeruginosa PAO1, PA3392 (nosZ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3392
Name
nosZ
Replicon chromosome
Genomic location 3797009 - 3798919 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252082.1
GI 15598588
Affymetrix PA3392_nosZ_at
Entrez 879824
GenBank AAG06780.1
INSDC AAG06780.1
NCBI Locus Tag PA3392
protein_id(GenBank) gb|AAG06780.1|AE004760_8|gnl|PseudoCAP|PA3392
TIGR NTL03PA03392
UniParc UPI0000130558
UniProtKB Acc Q9HYL2
UniProtKB ID NOSZ_PSEAE
UniRef100 UniRef100_Q9HYL2
UniRef50 UniRef50_Q51705
UniRef90 UniRef90_Q9HYL2

Product

Feature Type CDS
Coding Frame 1
Product Name
nitrous-oxide reductase precursor
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -6.25
Kyte-Doolittle Hydrophobicity Value -0.355
Molecular Weight (kDa) 70.7
Isoelectric Point (pI) 6.47

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Periplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 116 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002236 (351 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3392
Search term: nosZ

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Pseudomonas stutzeri N2O reductase contains CuA-type sites.
Scott RA, Zumft WG, Coyle CL, Dooley DM
Proc Natl Acad Sci U S A 1989 Jun;86(11):4082-6
PubMed ID: 2542963
Nitrous oxide reductase from denitrifying Pseudomonas stutzeri. Genes for copper-processing and properties of the deduced products, including a new member of the family of ATP/GTP-binding proteins.
Zumft WG, Viebrock-Sambale A, Braun C
Eur J Biochem 1990 Sep 24;192(3):591-9
PubMed ID: 2170125