Pseudomonas aeruginosa PAO1, PA3396 (nosL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3396
Name
nosL
Replicon chromosome
Genomic location 3801948 - 3802484 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252086.1
GI 15598592
Affymetrix PA3396_nosL_at
Entrez 879912
GenBank AAG06784.1
INSDC AAG06784.1
NCBI Locus Tag PA3396
protein_id(GenBank) gb|AAG06784.1|AE004760_12|gnl|PseudoCAP|PA3396
TIGR NTL03PA03396
UniParc UPI00000C59EB
UniProtKB Acc Q9HYK8
UniProtKB ID Q9HYK8_PSEAE
UniRef100 UniRef100_Q9HYK8
UniRef50 UniRef50_Q9HYK8
UniRef90 UniRef90_Q9HYK8

Product

Feature Type CDS
Coding Frame 1
Product Name
NosL protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -6.20
Kyte-Doolittle Hydrophobicity Value -0.239
Molecular Weight (kDa) 19.3
Isoelectric Point (pI) 5.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 74 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002232 (352 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3396
Search term: nosL
Search term: NosL protein

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Mutation of the conserved Cys165 outside of the CuA domain destabilizes nitrous oxide reductase but maintains its catalytic activity. Evidence for disulfide bridges and a putative protein disulfide isomerase gene.
Dreusch A, Riester J, Kroneck PM, Zumft WG
Eur J Biochem 1996 Apr 15;237(2):447-53
PubMed ID: 8647084