Pseudomonas aeruginosa PAO1, PA3617 (recA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3617
Name
recA
Replicon chromosome
Genomic location 4051564 - 4052604 (- strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252307.1
GI 15598813
Affymetrix PA3617_recA_at
DNASU PaCD00007583
Entrez 880173
GenBank AAG07005.1
INSDC AAG07005.1
NCBI Locus Tag PA3617
protein_id(GenBank) gb|AAG07005.1|AE004782_3|gnl|PseudoCAP|PA3617
TIGR NTL03PA03617
UniParc UPI0000133516
UniProtKB Acc P08280
UniProtKB ID RECA_PSEAE
UniRef100 UniRef100_A6V1H2
UniRef50 UniRef50_P16971
UniRef90 UniRef90_C1DSQ4

Product

Feature Type CDS
Coding Frame 1
Product Name
RecA protein
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Detected by MALDI-TOF/TOF (PMID:19333994).
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (36.88 kDa, PMID:21751344)
Charge (pH 7) -5.33
Kyte-Doolittle Hydrophobicity Value -0.131
Molecular Weight (kDa) 36.9
Isoelectric Point (pI) 5.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Vesicle Class 1
Cytoplasmic Class 1
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 646 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002057 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3617
Search term: recA
Search term: RecA protein

Human Homologs

References

The sequence and function of the recA gene and its protein in Pseudomonas aeruginosa PAO.
Sano Y, Kageyama M
Mol Gen Genet 1987 Jul;208(3):412-9
PubMed ID: 2823059
[Structure of the Pseudomonas aeruginosa recA gene].
Kriukov VM, Zaĭtsev EN, Kuz'min NP, Baev AA
Bioorg. Khim. 1990 Sep;16(9):1177-82
PubMed ID: 2127886
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344