Pseudomonas aeruginosa PAO1, PA3690

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3690
Name
Replicon chromosome
Genomic location 4131536 - 4133758 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252380.1
GI 15598886
Affymetrix PA3690_at
Entrez 879136
GenBank AAG07078.1
INSDC AAG07078.1
NCBI Locus Tag PA3690
protein_id(GenBank) gb|AAG07078.1|AE004788_8|gnl|PseudoCAP|PA3690
TIGR NTL03PA03690
UniParc UPI00000C5ABF
UniProtKB Acc Q9HXV0
UniProtKB ID Q9HXV0_PSEAE
UniRef100 UniRef100_Q9HXV0
UniRef50 UniRef50_A0A022P8N4
UniRef90 UniRef90_A0A022P8N4

Product

Feature Type CDS
Coding Frame 1
Product Name
probable metal-transporting P-type ATPase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -11.59
Kyte-Doolittle Hydrophobicity Value 0.177
Molecular Weight (kDa) 78.7
Isoelectric Point (pI) 5.93

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 643 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001987 (511 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3690

Human Homologs

Ensembl 110, assembly GRCh38.p14
ATPase copper transporting beta [Source:HGNC Symbol;Acc:HGNC:870]
E-value: 2.5e-68
Percent Identity: 32.6
Ensembl 110, assembly GRCh38.p14
ATPase copper transporting beta [Source:HGNC Symbol;Acc:HGNC:870]
E-value: 2.5e-68
Percent Identity: 32.6
Ensembl 110, assembly GRCh38.p14
ATPase copper transporting beta [Source:HGNC Symbol;Acc:HGNC:870]
E-value: 2.5e-68
Percent Identity: 32.6
Ensembl 110, assembly GRCh38.p14
ATPase copper transporting beta [Source:HGNC Symbol;Acc:HGNC:870]
E-value: 2.5e-68
Percent Identity: 32.6

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295