Pseudomonas aeruginosa PAO1, PA4619

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4619
Name
Replicon chromosome
Genomic location 5177655 - 5178902 (- strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 4 transposon mutants in orthologs

Cross-References

RefSeq NP_253309.1
GI 15599815
Affymetrix PA4619_at
Entrez 881146
GenBank AAG08007.1
INSDC AAG08007.1
NCBI Locus Tag PA4619
protein_id(GenBank) gb|AAG08007.1|AE004876_2|gnl|PseudoCAP|PA4619
TIGR NTL03PA04620
UniParc UPI00000C5D8F
UniProtKB Acc Q9HVH2
UniProtKB ID Q9HVH2_PSEAE
UniRef100 UniRef100_Q9HVH2
UniRef50 UniRef50_B1JBW3
UniRef90 UniRef90_Q9HVH2

Product

Feature Type CDS
Coding Frame 1
Product Name
probable c-type cytochrome
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -5.29
Kyte-Doolittle Hydrophobicity Value -0.269
Molecular Weight (kDa) 44.7
Isoelectric Point (pI) 6.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 135 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003225 (1168 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4619

Human Homologs

References

Characterization of the genes encoding the three-component membrane-bound alcohol dehydrogenase from Gluconobacter suboxydans and their expression in Acetobacter pasteurianus.
Kondo K, Horinouchi S
Appl Environ Microbiol 1997 Mar;63(3):1131-8
PubMed ID: 9055427