Pseudomonas aeruginosa PAO1, PA4753

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA4753
Name
Synonym: yhbY
Replicon chromosome
Genomic location 5338618 - 5338932 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253441.1
GI 15599947
Affymetrix PA4753_at
DNASU PaCD00008061
Entrez 881726
GenBank AAG08139.1
INSDC AAG08139.1
NCBI Locus Tag PA4753
protein_id(GenBank) gb|AAG08139.1|AE004889_2|gnl|PseudoCAP|PA4753
TIGR NTL03PA04754
UniParc UPI000013A30E
UniProtKB Acc P95453
UniProtKB ID Y4753_PSEAE
UniRef100 UniRef100_P95453
UniRef50 UniRef50_P95453
UniRef90 UniRef90_P95453

Product

Feature Type CDS
Coding Frame 1
Product Name
conserved hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 4.68
Kyte-Doolittle Hydrophobicity Value -0.341
Molecular Weight (kDa) 11.7
Isoelectric Point (pI) 10.06

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 222 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004398 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA4753

Human Homologs

References

Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.
Fleischmann RD, Adams MD, White O, Clayton RA, Kirkness EF, Kerlavage AR, Bult CJ, Tomb JF, Dougherty BA, Merrick JM
Science 1995 Jul 28;269(5223):496-512
PubMed ID: 7542800