Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4771
|
Name |
lldD
Synonym: lctD |
Replicon | chromosome |
Genomic location | 5357230 - 5358375 (+ strand) |
Transposon Mutants | 3 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 1 transposon mutants in orthologs |
Comment |
RefSeq | NP_253459.1 |
GI | 15599965 |
Affymetrix | PA4771_lldD_at |
DNASU | PaCD00008069 |
Entrez | 881809 |
GenBank | AAG08157.1 |
INSDC | AAG08157.1 |
NCBI Locus Tag | PA4771 |
protein_id(GenBank) | gb|AAG08157.1|AE004890_10|gnl|PseudoCAP|PA4771 |
TIGR | NTL03PA04772 |
UniParc | UPI00000C5DF8 |
UniProtKB Acc | Q9HV37 |
UniProtKB ID | LLDD_PSEAE |
UniRef100 | UniRef100_B7V1I3 |
UniRef50 | UniRef50_C3K053 |
UniRef90 | UniRef90_B7V1I3 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
L-lactate dehydrogenase
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected using LC-MS/MS (41.12 kDa, PMID:21751344)
|
Charge (pH 7) | -1.82 |
Kyte-Doolittle Hydrophobicity Value | 0.110 |
Molecular Weight (kDa) | 41.1 |
Isoelectric Point (pI) | 6.38 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 303 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004414 (448 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4771
Search term: lldD
Search term: L-lactate dehydrogenase
|
Ensembl
110, assembly
GRCh38.p14
|
hydroxyacid oxidase 1 [Source:HGNC Symbol;Acc:HGNC:4809]
E-value:
2.6e-56
Percent Identity:
35.5
|
Inducible membrane-bound L-lactate dehydrogenase from Escherichia coli. Purification and properties.
Futai M, Kimura H
J Biol Chem 1977 Aug 25;252(16):5820-7
PubMed ID: 18473
|
Effects of phospholipids on L-lactate dehydrogenase from membranes of Escherichia coli. Activation and stabilization of the enzyme with phospholipids.
Kimura H, Futai M
J Biol Chem 1978 Feb 25;253(4):1095-110
PubMed ID: 342518
|
Three overlapping lct genes involved in L-lactate utilization by Escherichia coli.
Dong JM, Taylor JS, Latour DJ, Iuchi S, Lin EC
J Bacteriol 1993 Oct;175(20):6671-8
PubMed ID: 8407843
|
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344
|
Two NAD-independent l-lactate dehydrogenases drive l-lactate utilization in Pseudomonas aeruginosa PAO1.
Wang Y, Xiao D, Liu Q, Zhang Y, Hu C, Sun J, Yang C, Xu P, Ma C, Gao C
Environ Microbiol Rep 2018 Oct;10(5):569-575
PubMed ID: 30066495
|