Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA4992
|
Name |
|
Replicon | chromosome |
Genomic location | 5607668 - 5608480 (+ strand) |
RefSeq | NP_253679.1 |
GI | 15600185 |
Affymetrix | PA4992_at |
DNASU | PaCD00008156 |
Entrez | 880167 |
GenBank | AAG08377.1 |
INSDC | AAG08377.1 |
NCBI Locus Tag | PA4992 |
protein_id(GenBank) | gb|AAG08377.1|AE004912_3|gnl|PseudoCAP|PA4992 |
TIGR | NTL03PA04993 |
UniParc | UPI00000C5EB5 |
UniProtKB Acc | Q9HUH3 |
UniProtKB ID | Q9HUH3_PSEAE |
UniRef100 | UniRef100_Q9HUH3 |
UniRef50 | UniRef50_Q9HUH3 |
UniRef90 | UniRef90_Q9HUH3 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
putative aldo-keto reductase
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | -2.89 |
Kyte-Doolittle Hydrophobicity Value | -0.101 |
Molecular Weight (kDa) | 29.0 |
Isoelectric Point (pI) | 6.43 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
4EXA | OXIDOREDUCTASE | 04/30/12 | Crystal structure of the PA4992, the putative aldo-keto reductase from Pseudomona aeruginosa | Pseudomonas aeruginosa PAO1 | 2.8 | X-RAY DIFFRACTION | 100.0 |
4EXB | OXIDOREDUCTASE | 04/30/12 | Putative aldo-keto reductase from Pseudomona aeruginosa | Pseudomonas aeruginosa | 2.75 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 501 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG004602 (537 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA4992
Search term: putative aldo-keto reductase
|
The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery.
Moynie L, Schnell R, McMahon SA, Sandalova T, Boulkerou WA, Schmidberger JW, Alphey M, Cukier C, Duthie F, Kopec J, Liu H, Jacewicz A, Hunter WN, Naismith JH, Schneider G
Acta Crystallogr Sect F Struct Biol Cryst Commun 2013 Jan 1;69(Pt 1):25-34
PubMed ID: 23295481
|