Pseudomonas aeruginosa PAO1, PA5008 (wapP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5008
Name
wapP
Synonym: waaP
Synonym: waaX
Replicon chromosome
Genomic location 5627131 - 5627865 (- strand)

Cross-References

RefSeq NP_253695.1
GI 15600201
Affymetrix PA5008_at
DNASU PaCD00008161
Entrez 881539
GenBank AAG08393.1
INSDC AAG08393.1
NCBI Locus Tag PA5008
protein_id(GenBank) gb|AAG08393.1|AE004913_8|gnl|PseudoCAP|PA5008
TIGR NTL03PA05009
UniParc UPI00000D4267
UniProtKB Acc G3XD48
UniProtKB ID G3XD48_PSEAE
UniRef100 UniRef100_W0Z176
UniRef50 UniRef50_G8Q3T8
UniRef90 UniRef90_A6VDC7

Product

Feature Type CDS
Coding Frame 1
Product Name
WapP
Product Name Confidence: Class 1
Synonyms hypothetical protein
WaaP
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 18.35
Kyte-Doolittle Hydrophobicity Value -0.655
Molecular Weight (kDa) 29.1
Isoelectric Point (pI) 10.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 12 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004615 (534 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5008
Search term: wapP
Search term: WapP

Human Homologs

References

Lipopolysaccharide (LPS) inner-core phosphates are required for complete LPS synthesis and transport to the outer membrane in Pseudomonas aeruginosa PAO1.
Delucia AM, Six DA, Caughlan RE, Gee P, Hunt I, Lam JS, Dean CR
mBio 2011;2(4)
PubMed ID: 21810964