Pseudomonas aeruginosa PAO1, PA5011 (waaC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5011
Name
waaC
Synonym: rfaC
Replicon chromosome
Genomic location 5629786 - 5630853 (- strand)
Transposon Mutants 1 transposon mutants in PAO1

Cross-References

RefSeq NP_253698.1
GI 15600204
Affymetrix PA5011_waaC_at
Entrez 881533
GenBank AAG08396.1
INSDC AAG08396.1
NCBI Locus Tag PA5011
protein_id(GenBank) gb|AAG08396.1|AE004913_11|gnl|PseudoCAP|PA5011
TIGR NTL03PA05012
UniParc UPI00000C5EC7
UniProtKB Acc Q9HUF5
UniProtKB ID Q9HUF5_PSEAE
UniRef100 UniRef100_Q9HUF5
UniRef50 UniRef50_P24173
UniRef90 UniRef90_A6VDD0

Product

Feature Type CDS
Coding Frame 1
Product Name
heptosyltransferase I
Product Name Confidence: Class 1
Synonyms Heptose I transferase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 8.50
Kyte-Doolittle Hydrophobicity Value -0.224
Molecular Weight (kDa) 39.7
Isoelectric Point (pI) 9.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 273 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004618 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5011
Search term: waaC

Human Homologs

References

Isolation and characterization of two genes, waaC (rfaC) and waaF (rfaF), involved in Pseudomonas aeruginosa serotype O5 inner-core biosynthesis.
de Kievit TR, Lam JS
J Bacteriol 1997 Jun;179(11):3451-7
PubMed ID: 9171387