Pseudomonas aeruginosa PAO1, PA5021

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5021
Name
Replicon chromosome
Genomic location 5647814 - 5649430 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_253708.3
GI 161486760
Affymetrix PA5021_at
Entrez 881272
GenBank AAG08406.1
INSDC AAG08406.1
NCBI Locus Tag PA5021
protein_id(GenBank) gb|AAG08406.1|AE004915_1|gnl|PseudoCAP|PA5021
TIGR NTL03PA05022
UniParc UPI00001C0410
UniProtKB Acc Q9HUE8
UniProtKB ID NHAP2_PSEAE
UniRef100 UniRef100_Q9HUE8
UniRef50 UniRef50_Q87KV8
UniRef90 UniRef90_Q9HUE8

Product

Feature Type CDS
Coding Frame 1
Product Name
probable sodium/hydrogen antiporter
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -3.96
Kyte-Doolittle Hydrophobicity Value 0.696
Molecular Weight (kDa) 57.2
Isoelectric Point (pI) 6.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 368 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004628 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5021

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295