Pseudomonas aeruginosa PAO1, PA5124 (ntrB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5124
Name
ntrB
Replicon chromosome
Genomic location 5772298 - 5773374 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_253811.1
GI 15600317
Affymetrix PA5124_ntrB_at
DNASU PaCD00008203
Entrez 877971
GenBank AAG08509.1
INSDC AAG08509.1
NCBI Locus Tag PA5124
protein_id(GenBank) gb|AAG08509.1|AE004925_7|gnl|PseudoCAP|PA5124
TIGR NTL03PA05125
UniParc UPI00000C5F14
UniProtKB Acc Q9HU60
UniProtKB ID Q9HU60_PSEAE
UniRef100 UniRef100_W0Z113
UniRef50 UniRef50_Q4KJR1
UniRef90 UniRef90_A6VDP2

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component sensor NtrB
Product Name Confidence: Class 1
Synonyms NR(II)
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -6.16
Kyte-Doolittle Hydrophobicity Value -0.161
Molecular Weight (kDa) 39.9
Isoelectric Point (pI) 6.09

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 608 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG004717 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5124
Search term: ntrB

Human Homologs

References

Nucleotide sequence of the Vibrio alginolyticus glnA region.
Maharaj R, Rumbak E, Jones WA, Robb SM, Robb FT, Woods DR
Arch Microbiol 1989;152(6):542-9
PubMed ID: 2574025
Swarming of Pseudomonas aeruginosa is controlled by a broad spectrum of transcriptional regulators, including MetR.
Yeung AT, Torfs EC, Jamshidi F, Bains M, Wiegand I, Hancock RE, Overhage J
J Bacteriol 2009 Sep;191(18):5592-602
PubMed ID: 19592586