Pseudomonas aeruginosa PAO1, PA5442
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAO1 (Reference)
GCF_000006765.1|latest |
| Locus Tag |
PA5442
|
| Name |
|
| Replicon | chromosome |
| Genomic location | 6128056 - 6130911 (- strand) |
| Transposon Mutants | 4 transposon mutants in PAO1 |
| Transposon Mutants in orthologs | 2 transposon mutants in orthologs |
| Comment | Overexpression of PA5442 impairs TTSS-mediated cytotoxicity |
Cross-References
| RefSeq | NP_254129.1 |
| GI | 15600635 |
| Affymetrix | PA5442_at |
| Entrez | 877848 |
| GenBank | AAG08827.1 |
| INSDC | AAG08827.1 |
| NCBI Locus Tag | PA5442 |
| protein_id(GenBank) | gb|AAG08827.1|AE004957_2|gnl|PseudoCAP|PA5442 |
| TIGR | NTL03PA05443 |
| UniParc | UPI00000C600B |
| UniProtKB Acc | Q9HTC4 |
| UniProtKB ID | Q9HTC4_PSEAE |
| UniRef100 | UniRef100_Q9HTC4 |
| UniRef50 | UniRef50_Q4K3G4 |
| UniRef90 | UniRef90_Q9HTC4 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
conserved hypothetical protein
|
| Synonyms | |
| Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
| Charge (pH 7) | 0.43 |
| Kyte-Doolittle Hydrophobicity Value | -0.087 |
| Molecular Weight (kDa) | 106.4 |
| Isoelectric Point (pI) | 7.04 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold Protein Structure Database
Available for P. aeruginosa PAO1.
| View predicted 3D structure in AlphaFold DB |
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 521 genera
|
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG004258 (1005 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PA5442
|
Human Homologs
References
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|