Pseudomonas aeruginosa PAO1, PA5454 (rmd)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5454
Name
rmd
Replicon chromosome
Genomic location 6144077 - 6144991 (- strand)
Transposon Mutants 5 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_254141.1
GI 15600647
Affymetrix PA5454_rmd_at
Entrez 883037
GenBank AAG08839.1
INSDC AAG08839.1
NCBI Locus Tag PA5454
protein_id(GenBank) gb|AAG08839.1|AE004958_9|gnl|PseudoCAP|PA5454
TIGR NTL03PA05455
UniParc UPI00000C6013
UniProtKB Acc Q9HTB6
UniProtKB ID RMD_PSEAE
UniRef100 UniRef100_Q9HTB6
UniRef50 UniRef50_Q9HTB6
UniRef90 UniRef90_Q9HTB6

Product

Feature Type CDS
Coding Frame 1
Product Name
oxidoreductase Rmd
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.65
Kyte-Doolittle Hydrophobicity Value -0.141
Molecular Weight (kDa) 33.9
Isoelectric Point (pI) 6.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6X3B OXIDOREDUCTASE 05/21/20 Structure of RMD from Pseudomonas aeruginosa complexed with NADPH Pseudomonas aeruginosa 1.91 X-RAY DIFFRACTION 99.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 636 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005000 (385 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5454
Search term: rmd

Human Homologs

Ensembl 110, assembly GRCh38.p14
GDP-mannose 4,6-dehydratase [Source:HGNC Symbol;Acc:HGNC:4369]
E-value: 5.6e-14
Percent Identity: 27.4
Ensembl 110, assembly GRCh38.p14
GDP-mannose 4,6-dehydratase [Source:HGNC Symbol;Acc:HGNC:4369]
E-value: 5.6e-14
Percent Identity: 27.4

References

No references are associated with this feature.