Pseudomonas aeruginosa PAO1, PA5476 (citA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5476
Name
citA
Replicon chromosome
Genomic location 6166120 - 6167409 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq NP_254163.1
GI 15600669
Affymetrix PA5476_citA_at
Entrez 878200
GenBank AAG08861.1
INSDC AAG08861.1
NCBI Locus Tag PA5476
protein_id(GenBank) gb|AAG08861.1|AE004960_4|gnl|PseudoCAP|PA5476
TIGR NTL03PA05477
UniParc UPI00000C6029
UniProtKB Acc Q9HT94
UniProtKB ID Q9HT94_PSEAE
UniRef100 UniRef100_Q9HT94
UniRef50 UniRef50_G8PYX3
UniRef90 UniRef90_A6VEU9

Product

Feature Type CDS
Coding Frame 1
Product Name
citrate transporter
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 4.62
Kyte-Doolittle Hydrophobicity Value 0.660
Molecular Weight (kDa) 46.2
Isoelectric Point (pI) 9.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 303 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003937 (894 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5476
Search term: citA

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Cloning and DNA sequence of a plasmid-determined citrate utilization system in Escherichia coli.
Sasatsu M, Misra TK, Chu L, Laddaga R, Silver S
J Bacteriol 1985 Dec;164(3):983-93
PubMed ID: 2999088