Pseudomonas aeruginosa PAO1, PA0009 (glyQ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0009
Name
glyQ
Replicon chromosome
Genomic location 12488 - 13435 (- strand)

Cross-References

RefSeq NP_064729.1
GI 15595207
Affymetrix PA0009_glyQ_at
Entrez 878095
GenBank AAG03399.1
INSDC AAG03399.1
NCBI Locus Tag PA0009
protein_id(GenBank) gb|AAG03399.1|AE004440_9|gnl|PseudoCAP|PA0009
TIGR NTL03PA00010
UniParc UPI0000136481
UniProtKB Acc Q9I7B7
UniProtKB ID SYGA_PSEAE
UniRef100 UniRef100_B7V0P4
UniRef50 UniRef50_P00960
UniRef90 UniRef90_Q4KKR7

Product

Feature Type CDS
Coding Frame 1
Product Name
glycyl-tRNA synthetase alpha chain
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Detected by MALDI-TOF/TOF (PMID:19333994).
Charge (pH 7) -11.62
Kyte-Doolittle Hydrophobicity Value -0.243
Molecular Weight (kDa) 36.1
Isoelectric Point (pI) 4.70

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 403 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000009 (538 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0009
Search term: glyQ

Human Homologs

References

Gene for Escherichia coli glycyl-tRNA synthetase has tandem subunit coding regions in the same reading frame.
Keng T, Webster TA, Sauer RT, Schimmel P
J Biol Chem 1982 Nov 10;257(21):12503-8
PubMed ID: 6290471
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994